Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 28205554
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030216 - keratinocyte differentiation
GO:0045736 - negative regulation of cyclin-dependent protein serine/threonine kinase activity
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 156
Hs

1 1088
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Service provided by Combinatics, Japan

Last updated: 11Aug2025