HitPredict

Interactor 1: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 11805826, 16284124, 16338358, 22215586, 26744777, 16429126, 26182356, 28106073, 26929360, 18314965, 34161281, 27405762, 31601863, 31848235, 30792173, 15917626, 21321079, 21627799, 21658604, 22237024 and 10 others

more...
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043248 - proteasome assembly
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 306
Sc

1 434
+ Dm
+ Hs
+ Sp
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ At
+ At
+ Ce
+ Mm
+ At
+ At
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Dm

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Last updated: 11Aug2025