HitPredict

Interactor 1: VAMP7 (P51809)
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)
Gene: VAMP7

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0031902 - late endosome membrane GO:0035577 - azurophil granule membrane GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 161
+	Hs
		180882 YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1152074 VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		261676 VAMP4_HUMAN (124-193): 2.11e-10: 58.5: 41.43		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00