HitPredict

Interactor 1: MSH6 (P52701)
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
Gene: MSH6

Interactor 2: PMS1 (P54277)
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)
Gene: PMS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10748159
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~MutS_II, HATPase_c_3~MutS_III, HATPase_c_3~MutS_V
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
GO:0019899 - enzyme binding
GO:0030983 - mismatched DNA binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1360
Hs

1 932
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024