HitPredict

Interactor 1: EFNA4 (P52798)
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Gene: EFNA4

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 33961781, 23686814, 19836338
Identification Methods affinity chromatography technology, surface plasmon resonance, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ephrin~Ephrin_lbd
Common GO terms GO:0005005 - transmembrane-ephrin receptor activity
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0046875 - ephrin receptor binding
GO:0048013 - ephrin receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 201
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Last updated: 15 Jul 2024