Protein: RRF2M
Ribosome-releasing factor 2, mitochondrial (RRF2mt) (EC 3.6.5.-) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2)

Gene: RRF2M, GFM2
Organism: Homo sapiens
Interactions: 173
UniProt ID: Q969S9

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0032543 - mitochondrial translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

882807

EFTU
Elongation factor Tu, mitochondrial

2

7

High-throughput

0.811

High

275333

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

3

1

High-throughput

0.667

High

914692

RM12
Large ribosomal subunit protein bL12m

3

3

High-throughput

0.667

High

946513

YBEY
Endoribonuclease YbeY

2

2

High-throughput

0.628

High

61969

GTPBA
GTP-binding protein 10

1

6

High-throughput

0.618

High

288985

ERAL1
GTPase Era, mitochondrial

1

8

High-throughput

0.618

High

1211786

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

1

High-throughput

0.611

High

349696

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.602

High

471163

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

2

3

High-throughput

0.584

High

1381137

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

2

High-throughput

0.574

High

572109

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.573

High

271080

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

3

High-throughput

0.536

High

869206

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

High-throughput

0.536

High

1242602

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

1

High-throughput

0.536

High

1381103

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

1

High-throughput

0.536

High

1381146

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

1381119

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

15

High-throughput

0.523

High

1278901

AT5L2
ATP synthase subunit g 2, mitochondrial

1

0

High-throughput

0.513

High

1381121

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

1357713

TRI41
E3 ubiquitin-protein ligase TRIM41

1

2

High-throughput

0.489

High

1381151

NPTN
Neuroplastin

1

4

High-throughput

0.489

High

61569

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

76004

B4DEF8
Large ribosomal subunit protein mL45

1

1

High-throughput

0.479

High

127521

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

2

High-throughput

0.479

High

143883

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

5

High-throughput

0.479

High

209798

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

1

High-throughput

0.479

High

221626

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

2

High-throughput

0.479

High

223855

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

3

High-throughput

0.479

High

242511

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

256340

RT14
Small ribosomal subunit protein uS14m

1

2

High-throughput

0.479

High

275707

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

2

High-throughput

0.479

High

278705

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

1

High-throughput

0.479

High

283921

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

2

High-throughput

0.479

High

298768

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

2

High-throughput

0.479

High

322278

GLSK
Glutaminase kidney isoform, mitochondrial

1

2

High-throughput

0.479

High

328557

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

1

High-throughput

0.479

High

329317

LETM1
Mitochondrial proton/calcium exchanger protein

1

2

High-throughput

0.479

High

359706

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

3

High-throughput

0.479

High

414358

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

443909

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

4

High-throughput

0.479

High

539379

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

8

High-throughput

0.479

High

560895

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

6

High-throughput

0.479

High

568461

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

617564

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

1

High-throughput

0.479

High

622232

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.479

High

665654

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

2

High-throughput

0.479

High

702640

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

1

High-throughput

0.479

High

716710

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

1

High-throughput

0.479

High

717123

ECHM
Enoyl-CoA hydratase, mitochondrial

1

7

High-throughput

0.479

High

719453

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

7

High-throughput

0.479

High

733969

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

5

High-throughput

0.479

High

760979

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

3

High-throughput

0.479

High

788129

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

8

High-throughput

0.479

High

793730

ETFB
Electron transfer flavoprotein subunit beta

1

2

High-throughput

0.479

High

841856

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

869935

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

2

High-throughput

0.479

High

882349

RM19
Large ribosomal subunit protein bL19m

1

1

High-throughput

0.479

High

888728

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

3

High-throughput

0.479

High

890995

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

1

High-throughput

0.479

High

902545

RT29
Small ribosomal subunit protein mS29

1

2

High-throughput

0.479

High

926102

DPOG1
DNA polymerase subunit gamma-1

1

1

High-throughput

0.479

High

940034

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

1

High-throughput

0.479

High

941688

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

1

High-throughput

0.479

High

1011138

RT22
Small ribosomal subunit protein mS22

1

2

High-throughput

0.479

High

1011336

RT25
Small ribosomal subunit protein mS25

1

2

High-throughput

0.479

High

1011495

RT10
Small ribosomal subunit protein uS10m

1

5

High-throughput

0.479

High

1011674

RT35
Small ribosomal subunit protein mS35

1

2

High-throughput

0.479

High

1011858

RT05
Small ribosomal subunit protein uS5m

1

5

High-throughput

0.479

High

1012078

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

1

High-throughput

0.479

High

1012571

RT34
Small ribosomal subunit protein mS34

1

2

High-throughput

0.479

High

1012734

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.479

High

1012918

RT09
Small ribosomal subunit protein uS9m

1

3

High-throughput

0.479

High

1035423

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

3

High-throughput

0.479

High

1087478

GRSF1
G-rich sequence factor 1

1

16

High-throughput

0.479

High

1094071

RM28
Large ribosomal subunit protein bL28m

1

2

High-throughput

0.479

High

1104039

RM49
Large ribosomal subunit protein mL49

1

2

High-throughput

0.479

High

1108000

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

1138863

SYLM
Leucine--tRNA ligase, mitochondrial

1

8

High-throughput

0.479

High

1141524

OXA1L
Mitochondrial inner membrane protein OXA1L

1

1

High-throughput

0.479

High

1142750

PDK3
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1162202

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

2

High-throughput

0.479

High

1163487

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

2

High-throughput

0.479

High

1205125

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

1

High-throughput

0.479

High

1212519

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

2

High-throughput

0.479

High

1215601

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

1

High-throughput

0.479

High

1245974

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

2

High-throughput

0.479

High

1271104

TM10C
tRNA methyltransferase 10 homolog C

1

2

High-throughput

0.479

High

1271478

DHX30
ATP-dependent RNA helicase DHX30

1

6

High-throughput

0.479

High

1275803

RM21
Large ribosomal subunit protein bL21m

1

1

High-throughput

0.479

High

1281302

RM10
Large ribosomal subunit protein uL10m

1

1

High-throughput

0.479

High

1287516

RM52
Large ribosomal subunit protein mL52

1

1

High-throughput

0.479

High

1287624

ACOT1
Acyl-coenzyme A thioesterase 1

1

3

High-throughput

0.479

High

1312719

RM41
Large ribosomal subunit protein mL41

1

2

High-throughput

0.479

High

1323209

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

1

1

High-throughput

0.479

High

1324157

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.479

High

1328245

RM50
Large ribosomal subunit protein mL50

1

1

High-throughput

0.479

High

1331651

RM43
Large ribosomal subunit protein mL43

1

3

High-throughput

0.479

High

1335900

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

1

2

High-throughput

0.479

High

1347029

G45IP
Large ribosomal subunit protein mL64

1

1

High-throughput

0.479

High

1349913

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

6

High-throughput

0.479

High

1364339

RT27
Small ribosomal subunit protein mS27

1

2

High-throughput

0.479

High

1366386

RT31
Small ribosomal subunit protein mS31

1

2

High-throughput

0.479

High

1381100

RM24
Large ribosomal subunit protein uL24m

1

2

High-throughput

0.479

High

1381101

P5CR2
Pyrroline-5-carboxylate reductase 2

1

5

High-throughput

0.479

High

1381102

MTEF3
Transcription termination factor 3, mitochondrial

1

1

High-throughput

0.479

High

1381104

RT24
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

1381105

RM53
Large ribosomal subunit protein mL53

1

1

High-throughput

0.479

High

1381106

PTCD3
Small ribosomal subunit protein mS39

1

2

High-throughput

0.479

High

1381107

MMAB
Corrinoid adenosyltransferase MMAB

1

1

High-throughput

0.479

High

1381108

PEO1
Twinkle mtDNA helicase

1

2

High-throughput

0.479

High

1381109

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

2

High-throughput

0.479

High

1381110

TACO1
Translational activator of cytochrome c oxidase 1

1

2

High-throughput

0.479

High

1381111

CQ080
Mitochondrial nucleoid-associated protein 1

1

1

High-throughput

0.479

High

1381112

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

1381113

RM20
Large ribosomal subunit protein bL20m

1

1

High-throughput

0.479

High

1381114

RM13
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.479

High

1381115

RM09
Large ribosomal subunit protein bL9m

1

1

High-throughput

0.479

High

1381116

RM04
Large ribosomal subunit protein uL4m

1

3

High-throughput

0.479

High

1381117

RT26
Small ribosomal subunit protein mS26

1

2

High-throughput

0.479

High

1381118

RM37
Large ribosomal subunit protein mL37

1

1

High-throughput

0.479

High

1381120

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

12

High-throughput

0.479

High

1381122

RM46
Large ribosomal subunit protein mL46

1

2

High-throughput

0.479

High

1381124

RM44
Large ribosomal subunit protein mL44

1

2

High-throughput

0.479

High

1381126

RM47
Large ribosomal subunit protein uL29m

1

2

High-throughput

0.479

High

1381127

RT30
Large ribosomal subunit protein mL65

1

1

High-throughput

0.479

High

1381128

RM17
Large ribosomal subunit protein bL17m

1

1

High-throughput

0.479

High

1381129

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

7

High-throughput

0.479

High

1381131

RM39
Large ribosomal subunit protein mL39

1

3

High-throughput

0.479

High

1381132

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

6

High-throughput

0.479

High

1381133

RM15
Large ribosomal subunit protein uL15m

1

1

High-throughput

0.479

High

1381134

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

1

High-throughput

0.479

High

1381135

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.479

High

1381136

STML2
Stomatin-like protein 2, mitochondrial

1

1

High-throughput

0.479

High

1381138

BCS1
Mitochondrial chaperone BCS1

1

10

High-throughput

0.479

High

1381140

RT33
Small ribosomal subunit protein mS33

1

2

High-throughput

0.479

High

1381142

RT28
Small ribosomal subunit protein bS1m

1

2

High-throughput

0.479

High

1381143

RT17
Small ribosomal subunit protein uS17m

1

2

High-throughput

0.479

High

1381144

RT07
Small ribosomal subunit protein uS7m

1

4

High-throughput

0.479

High

1381145

PDIP2
Polymerase delta-interacting protein 2

1

4

High-throughput

0.479

High

1381147

RT02
Small ribosomal subunit protein uS2m

1

5

High-throughput

0.479

High

1381148

RT16
Small ribosomal subunit protein bS16m

1

2

High-throughput

0.479

High

1381149

RT23
Small ribosomal subunit protein mS23

1

2

High-throughput

0.479

High

1381150

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

2

High-throughput

0.479

High

1381152

RT18B
Small ribosomal subunit protein mS40

1

2

High-throughput

0.479

High

1381153

NFS1
Cysteine desulfurase

1

1

High-throughput

0.479

High

1381154

RM42
Large ribosomal subunit protein mL42

1

1

High-throughput

0.479

High

1310289

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

76240

B4DJ38
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

3

High-throughput

0.437

High

794568

RBMX
RNA-binding motif protein, X chromosome

1

7

High-throughput

0.437

High

897360

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.437

High

965144

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.437

High

988176

TRA2B
Transformer-2 protein homolog beta

1

10

High-throughput

0.437

High

1099005

SRSF9
Serine/arginine-rich splicing factor 9

1

7

High-throughput

0.437

High

1111829

TRA2A
Transformer-2 protein homolog alpha

1

5

High-throughput

0.437

High

1153867

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.437

High

1254944

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1324035

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.437

High

1381123

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

430207

JUN
Transcription factor Jun

1

6

High-throughput

0.407

High

844850

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.407

High

1314348

SLX4
Structure-specific endonuclease subunit SLX4

1

5

High-throughput

0.407

High

1366160

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.407

High

1381139

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.407

High

1323315

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

0

High-throughput

0.299

High

1331998

BANP
Protein BANP

1

0

High-throughput

0.299

High

127712

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.279

Low

219211

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low

1235437

LCN8
Epididymal-specific lipocalin-8

1

0

High-throughput

0.279

Low

1381125

B2L12
Bcl-2-like protein 12

1

0

High-throughput

0.279

Low

1381130

BEX4
Protein BEX4

1

0

High-throughput

0.279

Low

352789

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.251

Low

1135499

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

1381141

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025