Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: UBP33 (Q8TEY7)
Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1) (hVDU1)
Gene: USP33

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37714834
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~zf-UBP, Ank_2~zf-UBP
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 942
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Last updated: 11Aug2025