HitPredict

Interactor 1: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1430 Hs			1 999
+	Rn
		506752 KCC2A_RAT (1-383): 5.07e-120: 385: 29.17		HYOU1_RAT (1-999): 0: 848: 91.69
+	Rn
		506757 KCC2A_RAT (1-383): 5.07e-120: 385: 29.17		HS105_RAT (33-968): 0: 807: 24.89
+	Hs
		714406 MYLK2_HUMAN (1-320): 1.18e-66: 239: 38.72		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		883688 RIPK4_HUMAN (635-957): 2.79e-33: 141: 13.99		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1330902 Q9H4D1_HUMAN (635-957): 5.06e-33: 140: 13.99		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320835 RIPK4_HUMAN (635-957): 2.79e-33: 141: 13.99		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320911 Q9H4D1_HUMAN (635-957): 5.06e-33: 140: 13.99		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		714162 RIPK4_HUMAN (635-957): 2.79e-33: 141: 13.99		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		714414 Q9H4D1_HUMAN (635-957): 5.06e-33: 140: 13.99		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		503916 ANK2_HUMAN (248-797): 3.54e-109: 385: 19.42		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504975 KCC2A_HUMAN (1-383): 6.29e-120: 385: 29.17		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		483759 ANK2_HUMAN (248-797): 3.54e-109: 385: 19.42		HS71A_HUMAN (682-813): 3.35e-30: 129: 16.67
+	Hs
		504037 KCC2D_HUMAN (2-383): 1.06e-116: 377: 27.94		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504743 MYLK2_HUMAN (1-320): 1.18e-66: 239: 38.72		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503777 RIPK4_HUMAN (635-957): 2.79e-33: 141: 13.99		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504758 Q9H4D1_HUMAN (635-957): 5.06e-33: 140: 13.99		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		564048 RIPK4_HUMAN (635-957): 2.79e-33: 141: 13.99		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		564185 Q9H4D1_HUMAN (635-957): 5.06e-33: 140: 13.99		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		714021 ANKK1_HUMAN (641-916): 1.43e-26: 119: 8.94		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04