HitPredict

Interactor 1: SMC3 (P47037)
Structural maintenance of chromosomes protein 3 (DA-box protein SMC3)
Gene: SMC3

Interactor 2: NUM1 (Q00402)
Nuclear migration protein NUM1
Gene: NUM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.548

Property	Details
Experiments	11087867, 38781029
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1230 Sc			1 2748
+	Sp
		205963 SMC3_SCHPO (1-1223): 4.18e-80: 289: 33.12		SMC3_SCHPO (60-490): 1.25e-52: 206: 13.96
+	Sp
		205965 SMC1_SCHPO (2-1215): 3.11e-66: 247: 16.07		SMC3_SCHPO (60-490): 1.25e-52: 206: 13.96
+	Sc
		864355 SMC3_YEAST (1-1230): 1.82e-109: 374: 100.00		SMC3_YEAST (8-792): 3.26e-09: 64.8: 14.61
+	Hs
		776872 SMC3_HUMAN (1-1228): 2.8e-92: 325: 30.28		MYH11_HUMAN (546-1423): 1.86e-19: 98.7: 12.61
+	Hs
		1462729 SMC3_HUMAN (1-1228): 2.8e-92: 325: 30.28		SMC3_HUMAN (8-869): 7.35e-18: 93.4: 13.72
+	Xl
		313484 SMC3_XENLA (1-1228): 3.73e-91: 322: 30.23		SMC3_XENLA (56-447): 2.22e-14: 81.8: 14.21
+	Hs
		1143309 SMC3_HUMAN (1-1228): 2.8e-92: 325: 30.28		PLEC_HUMAN (171-1277): 3.8e-09: 64.8: 11.93
+	Hs
		334127 SMC2_HUMAN (1-1229): 8.01e-77: 279: 18.37		SMC3_HUMAN (8-869): 7.35e-18: 93.4: 13.72
+	Mm
		1423807 SMC1A_MOUSE (2-1222): 1.46e-69: 257: 16.29		SMC3_MOUSE (8-869): 3.77e-18: 94.5: 13.83
+	Bt
		357658 SMC1A_BOVIN (2-1222): 1.79e-69: 257: 16.37		SMC3_BOVIN (8-869): 5.33e-18: 93.7: 13.72
+	Hs
		1130223 SMC1A_HUMAN (2-1222): 1.81e-69: 257: 16.37		SMC3_HUMAN (8-869): 7.35e-18: 93.4: 13.72
+	Hs
		1336791 SMC1B_HUMAN (2-1228): 8.17e-65: 243: 16.11		SMC3_HUMAN (8-869): 7.35e-18: 93.4: 13.72
+	Mm
		1362489 SMC1B_MOUSE (2-1228): 1.69e-61: 232: 16.21		SMC3_MOUSE (8-869): 3.77e-18: 94.5: 13.83
+	Xl
		313473 SMC1A_XENLA (2-1222): 8.83e-65: 243: 15.99		SMC3_XENLA (56-447): 2.22e-14: 81.8: 14.21
+	Xl
		313481 SMC1A_XENLA (2-1222): 8.83e-65: 243: 15.99		Q8AW91_XENLA (56-447): 2.75e-14: 81.8: 13.97
+	Sc
		747737 SMC1_YEAST (2-1215): 1.13e-69: 258: 16.16		SMC3_YEAST (8-792): 3.26e-09: 64.8: 14.61
+	Hs
		1130064 SMC1A_HUMAN (2-1222): 1.81e-69: 257: 16.37		FIL1L_HUMAN (110-425): 6.48e-09: 64: 20.24
+	Sc
		864388 SMC4_YEAST (1-1218): 1.95e-65: 245: 15.82		SMC3_YEAST (8-792): 3.26e-09: 64.8: 14.61
+	Sc
		808594 SMC2_YEAST (1-1210): 2.44e-62: 234: 17.73		SMC3_YEAST (8-792): 3.26e-09: 64.8: 14.61
+	Hs
		772645 MYH10_HUMAN (66-622): 2.73e-17: 90.1: 11.79		MYH9_HUMAN (691-1414): 1.28e-10: 69.8: 13.80