HitPredict

Interactor 1: NU192 (P47054)
Nucleoporin NUP192 (Nuclear pore protein NUP192)
Gene: NUP192

Interactor 2: NU116 (Q02630)
Nucleoporin NUP116/NSP116 (Nuclear pore protein NUP116/NSP116)
Gene: NUP116

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	26344569, 18046405, 10684247, 29033133, 27194810
Identification Methods	pull down, affinity chromatography technology, biochemical, two hybrid array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006913 - nucleocytoplasmic transport GO:0006999 - nuclear pore organization GO:0017056 - structural constituent of nuclear pore
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1683 Sc			1 1113
+	Sc
		864643 NU192_YEAST (1-1683): 0: 1682: 100.00		NU100_YEAST (117-1108): 1.66e-71: 259: 21.97
+	Sc
		634253 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP1_YEAST (124-918): 1.56e-24: 113: 10.35
+	Sc
		577315 NU192_YEAST (1-1683): 0: 1682: 100.00		NSP1_YEAST (524-969): 1.31e-14: 80.8: 12.25
+	Sc
		864635 NU192_YEAST (1-1683): 0: 1682: 100.00		NU145_YEAST (310-676): 2.77e-14: 80.1: 16.35
+	Sc
		864633 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP57_YEAST (272-533): 3.71e-10: 65.9: 29.43
+	Sc
		825157 NU192_YEAST (1-1683): 0: 1682: 100.00		NU159_YEAST (427-950): 1.01e-09: 65: 10.15
+	Sc
		864641 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP49_YEAST (168-386): 4.57e-09: 62.1: 29.92
+	Sc
		864634 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP42_YEAST (2-349): 8.67e-09: 61.1: 18.68
+	Hs
		916008 NU205_HUMAN (23-1642): 0: 1308: 15.72		NUP98_HUMAN (2-641): 7.31e-42: 170: 18.35
+	Hs
		775583 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU214_HUMAN (80-951): 7.83e-23: 108: 9.01
+	Hs
		890379 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU153_HUMAN (201-778): 1.98e-12: 73.9: 11.03
+	Xl
		1204263 Q642R6_XENLA (24-1642): 0: 1216: 15.16		Q5EWX9_XENLA (239-746): 4.6e-25: 115: 11.61
+	Tt
		107524 NU192_CHATD (24-1644): 0: 1131: 20.07		NU145_CHATD (2-719): 4.22e-13: 76.2: 17.13
+	Tt
		107522 NU192_CHATD (24-1644): 0: 1131: 20.07		NUP49_CHATD (386-575): 5.36e-09: 62.1: 32.66
+	Hs
		915973 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NUP98_HUMAN (2-641): 7.31e-42: 170: 18.35
+	Hs
		775553 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU214_HUMAN (80-951): 7.83e-23: 108: 9.01
+	Hs
		890336 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU153_HUMAN (201-778): 1.98e-12: 73.9: 11.03