HitPredict

Interactor 1: RP3A (P47708)
Rabphilin-3A (Exophilin-1)
Gene: Rph3a

Interactor 2: RB27A (Q9ERI2)
Ras-related protein Rab-27A (EC 3.6.5.2)
Gene: Rab27a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	12578829, 11773082, 14722103
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0030141 - secretory granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 681 Mm			1 221
+	Mm
		770469 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3D_MOUSE (2-221): 7.11e-86: 255: 40.46
+	Mm
		866419 RP3A_MOUSE (1-681): 0: 642: 100.00		RB27B_MOUSE (1-221): 5.21e-81: 242: 71.49
+	Hs
		902307 RP3A_HUMAN (1-681): 0: 591: 85.71		RB27A_HUMAN (1-221): 9.68e-86: 254: 95.93
+	Hs
		126013 RP3A_HUMAN (1-681): 0: 591: 85.71		RB27B_HUMAN (1-221): 1.33e-81: 244: 71.95
+	Mm
		866414 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3A_MOUSE (2-192): 9.54e-57: 181: 43.98
+	Mm
		866413 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3C_MOUSE (2-190): 2.84e-56: 180: 43.92
+	Mm
		866420 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3B_MOUSE (2-190): 3.03e-55: 177: 44.44
+	Mm
		866412 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB8A_MOUSE (6-187): 1.16e-53: 172: 46.70
+	Rn
		866423 RP3A_RAT (1-681): 0: 626: 97.37		RAB3A_RAT (2-192): 9.54e-57: 181: 43.98
+	Hs
		630450 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB3A_HUMAN (2-192): 8.94e-57: 181: 43.98
+	Hs
		630670 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB3B_HUMAN (2-190): 1.88e-54: 175: 43.92
+	Hs
		956029 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB8A_HUMAN (6-187): 9.23e-54: 172: 46.70
+	Hs
		1370785 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB8B_HUMAN (6-192): 3.91e-53: 171: 44.39
+	Dm
		304433 Q9W2R9_DROME (3-677): 3.13e-139: 423: 29.42		O76901_DROME (11-186): 5.21e-79: 238: 61.36
+	Hs
		902287 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RB27A_HUMAN (1-221): 9.68e-86: 254: 95.93
+	Hs
		126003 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RB27B_HUMAN (1-221): 1.33e-81: 244: 71.95
+	Hs
		630433 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3A_HUMAN (2-192): 8.94e-57: 181: 43.98
+	Hs
		343187 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3D_HUMAN (2-190): 1.76e-56: 180: 43.92
+	Hs
		630605 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3B_HUMAN (2-190): 1.88e-54: 175: 43.92
+	Hs
		955988 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB8A_HUMAN (6-187): 9.23e-54: 172: 46.70