HitPredict

Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 17082820, 32814053
Identification Methods pull down, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Josephin~ubiquitin, UIM~ubiquitin
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 361
Hs

1 589
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024