HitPredict

Interactor 1: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Interactor 2: SEPT2 (P54359)
Septin-2
Gene: Septin2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0007298 - border follicle cell migration GO:0007349 - cellularization GO:0008104 - intracellular protein localization and 1 others more... GO:0042060 - wound healing
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 192 Dm			1 419
+	Hs
		988780 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		SEP10_HUMAN (11-418): 0: 543: 66.35
+	Hs
		955435 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEPT8_HUMAN (2-418): 0: 550: 66.20
+	Hs
		955697 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEP10_HUMAN (11-418): 0: 543: 66.35
+	Hs
		955154 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEPT6_HUMAN (4-418): 0: 535: 67.22
+	Hs
		955214 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEPT7_HUMAN (20-419): 0: 532: 40.83
+	Dm
		828107 RHO1_DROME (1-192): 2.32e-77: 231: 100.00		PNUT_DROME (12-416): 0: 522: 36.56
+	Hs
		978034 RHOB_HUMAN (1-190): 3.26e-73: 220: 82.11		SEPT7_HUMAN (20-419): 0: 532: 40.83
+	Hs
		955660 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEP11_HUMAN (1-401): 0: 526: 71.57
+	Hs
		978344 RHOB_HUMAN (1-190): 3.26e-73: 220: 82.11		SEP11_HUMAN (1-401): 0: 526: 71.57
+	Dm
		837943 RHO1_DROME (1-192): 2.32e-77: 231: 100.00		SEPT1_DROME (13-349): 5.42e-161: 459: 42.82
+	Hs
		1015447 RHOG_HUMAN (1-192): 5.58e-77: 230: 55.21		SEPT2_HUMAN (10-352): 8.33e-160: 456: 40.91
+	Hs
		955181 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEPT2_HUMAN (10-352): 8.33e-160: 456: 40.91
+	Hs
		978015 RHOB_HUMAN (1-190): 3.26e-73: 220: 82.11		SEPT2_HUMAN (10-352): 8.33e-160: 456: 40.91
+	Hs
		955725 CDC42_HUMAN (1-192): 7.74e-75: 225: 53.89		SEPT9_HUMAN (22-306): 2.32e-147: 432: 42.81