HitPredict

Interactor 1: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1037 Hs			1 1343
+	Hs
		872693 EPHA4_HUMAN (33-1035): 0: 1223: 62.04		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1072624 EPHA7_HUMAN (37-1035): 0: 1222: 62.69		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		596384 EPHA4_HUMAN (33-1035): 0: 1223: 62.04		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		596362 EPHB2_HUMAN (60-1034): 0: 1209: 56.80		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		596383 EPHB3_HUMAN (57-1037): 0: 1155: 54.13		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		596361 EPHA2_HUMAN (58-1037): 0: 1105: 50.86		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		598429 EPHA2_HUMAN (58-1037): 0: 1105: 50.86		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598423 EPHA1_HUMAN (47-1028): 0: 995: 41.78		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		412315 FYN_HUMAN (669-933): 3.12e-64: 229: 44.20		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		433821 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		434065 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		435533 IGF1R_HUMAN (294-1017): 7.97e-145: 469: 23.00		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		609394 FGFR3_HUMAN (404-988): 2.12e-147: 461: 21.80		IQGA3_HUMAN (214-824): 5.56e-119: 409: 12.04
+	Hs
		442830 HCK_HUMAN (653-933): 1.21e-65: 232: 42.76		RASA3_HUMAN (157-681): 2.29e-131: 427: 21.64
+	Hs
		433762 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		RASA3_HUMAN (157-681): 2.29e-131: 427: 21.64
+	Hs
		442777 HCK_HUMAN (653-933): 1.21e-65: 232: 42.76		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Mm
		639459 LYN_MOUSE (659-933): 3.02e-65: 231: 43.68		Q91YX7_MOUSE (184-699): 8.5e-132: 427: 24.20
+	Hs
		433641 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		433751 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		IQGA2_HUMAN (216-848): 1.05e-121: 416: 14.05
+	Hs
		433572 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21