HitPredict

Interactor 1: S12A2 (P55011)
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2)
Gene: SLC12A2

Interactor 2: LEG9C (Q6DKI2)
Galectin-9C (Gal-9C) (Galectin-9-like protein B)
Gene: LGALS9C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1212 Hs			1 356
+	Hs
		873928 S12A2_HUMAN (1-1212): 0: 1285: 100.00		LEG9B_HUMAN (1-356): 1.44e-146: 419: 98.88
+	Hs
		119282 S12A2_HUMAN (1-1212): 0: 1285: 100.00		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Hs
		121133 S12A2_HUMAN (1-1212): 0: 1285: 100.00		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		572325 S12A2_HUMAN (1-1212): 0: 1285: 100.00		LEG3_HUMAN (4-148): 6.75e-42: 148: 37.50
+	Hs
		1150403 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG9C_HUMAN (1-356): 4.7e-148: 423: 100.00
+	Hs
		1107986 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG9B_HUMAN (1-356): 1.44e-146: 419: 98.88
+	Hs
		1150404 S12A4_HUMAN (167-1212): 0: 914: 23.71		LEG9C_HUMAN (1-356): 4.7e-148: 423: 100.00
+	Hs
		1107988 S12A4_HUMAN (167-1212): 0: 914: 23.71		LEG9B_HUMAN (1-356): 1.44e-146: 419: 98.88
+	Hs
		119555 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Hs
		119565 S12A4_HUMAN (167-1212): 0: 914: 23.71		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Hs
		119583 S12A7_HUMAN (163-1212): 0: 874: 22.62		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Hs
		121226 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		121232 S12A4_HUMAN (167-1212): 0: 914: 23.71		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		121236 S12A7_HUMAN (163-1212): 0: 874: 22.62		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		572474 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG3_HUMAN (4-148): 6.75e-42: 148: 37.50
+	Hs
		572481 S12A4_HUMAN (167-1212): 0: 914: 23.71		LEG3_HUMAN (4-148): 6.75e-42: 148: 37.50
+	Hs
		449377 S12A6_HUMAN (148-1212): 0: 918: 22.65		LEG1_HUMAN (235-354): 2.01e-34: 125: 32.00
+	Hs
		572490 S12A7_HUMAN (163-1212): 0: 874: 22.62		LEG3_HUMAN (4-148): 6.75e-42: 148: 37.50
+	Hs
		815062 S12A7_HUMAN (163-1212): 0: 874: 22.62		LEG7_HUMAN (225-355): 2.3e-39: 137: 38.52
+	Hs
		449398 S12A7_HUMAN (163-1212): 0: 874: 22.62		LEG1_HUMAN (235-354): 2.01e-34: 125: 32.00