Interactor 1: AF10 (P55197)
Protein AF-10 (ALL1-fused gene from chromosome 10 protein)
Gene: MLLT10

Interactor 2: DOT1L (Q8TEK3)
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
Gene: DOT1L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.735

The method score is based on:

Property Details
Experiments 20203130, 15851025, 26496610, 24981860, 20431927, 21103407
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032991 - protein-containing complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1068
Hs

1 1537
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024