HitPredict

Interactor 1: FOXG1 (P55316)
Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3)
Gene: FOXG1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15286281
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 489 Hs			1 2414
+	Hs
		964170 FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998614 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		952801 FOXK1_HUMAN (71-309): 9.43e-50: 183: 31.15		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998627 FOXI1_HUMAN (58-440): 1.76e-52: 183: 27.20		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		206831 FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Mm
		70946 FOXO3_MOUSE (59-468): 2.9e-47: 175: 20.35		EP300_MOUSE (1-2414): 0: 1090: 93.01
+	Hs
		877654 FOXG1_HUMAN (1-489): 9.66e-156: 453: 100.00		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		1021274 FOXI1_HUMAN (58-440): 1.76e-52: 183: 27.20		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		877985 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		1021269 FOXI1_HUMAN (58-440): 1.76e-52: 183: 27.20		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		877952 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		877735 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		964171 FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		1217546 FOXP4_HUMAN (55-340): 6.09e-54: 194: 27.59		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86
+	Hs
		1016224 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		1021235 FOXI1_HUMAN (58-440): 1.76e-52: 183: 27.20		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Hs
		1021242 FOXI1_HUMAN (58-440): 1.76e-52: 183: 27.20		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		877807 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Hs
		206847 FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Mm
		101473 FOXO3_MOUSE (59-468): 2.9e-47: 175: 20.35		F8VPR5_MOUSE (1752-2401): 7.8e-10: 67.1: 12.31