Protein: CCN6
Cellular communication network factor 6 (CCN family member 6) (WNT1-inducible-signaling pathway protein 3) (WISP-3)

Gene: CCN6
Organism: Homo sapiens
Interactions: 20
UniProt ID: O95389

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005615 - extracellular space
GO:0005739 - mitochondrion
GO:0007155 - cell adhesion
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335362

CREL2
Protein disulfide isomerase CRELD2

3

5

High-throughput

0.667

High

335364

SORL
Sortilin-related receptor

2

4

High-throughput

0.611

High

335357

NOTC1
Neurogenic locus notch homolog protein 1

1

4

High-throughput

0.536

High

335370

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

1

High-throughput

0.536

High

335354

CO6A2

1

0

High-throughput

0.513

High

287504

LRP6
Low-density lipoprotein receptor-related protein 6

1

5

High-throughput

0.489

High

335353

LDLR
Low-density lipoprotein receptor

1

6

High-throughput

0.489

High

335360

NOTC2
Neurogenic locus notch homolog protein 2

1

4

High-throughput

0.489

High

335363

FRAS1
Extracellular matrix organizing protein FRAS1

1

6

High-throughput

0.489

High

335368

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.489

High

335355

BRAF
Serine/threonine-protein kinase B-raf

1

0

High-throughput

0.458

High

335356

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.458

High

335365

APBB2
Amyloid beta precursor protein binding family B member 2

3

0

High-throughput

0.347

High

335369

DDX47
Probable ATP-dependent RNA helicase DDX47

3

0

High-throughput

0.347

High

335367

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.292

High

192769

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.279

Low

335358

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

335366

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

335359

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

335361

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025