HitPredict

Interactor 1: CENPF (P49454)
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
Gene: CENPF

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	17043677, 17600710, unassigned1973
Identification Methods	two hybrid, affinity chromatography technology, pull down, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005819 - spindle GO:0005829 - cytosol GO:0007059 - chromosome segregation and 1 others more... GO:0008017 - microtubule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3114 Hs			1 345
+	Hs
		883954 CENPF_HUMAN (1-3114): 0: 759: 100.00		NDE1_HUMAN (3-321): 2.96e-41: 149: 55.25
+	Hs
		157094 CENPF_HUMAN (1-3114): 0: 759: 100.00		CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32
+	Hs
		1414972 CP250_HUMAN (8-1717): 3.36e-63: 243: 11.47		NDE1_HUMAN (3-321): 2.96e-41: 149: 55.25
+	Hs
		1408531 AKAP9_HUMAN (1201-3083): 1.68e-32: 142: 9.38		NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00
+	Hs
		772991 CP250_HUMAN (8-1717): 3.36e-63: 243: 11.47		MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57
+	Hs
		1105663 GOGA4_HUMAN (1-1417): 2.76e-46: 187: 11.16		MYO10_HUMAN (36-324): 1.74e-29: 121: 15.92
+	Hs
		157329 GOGA4_HUMAN (1-1417): 2.76e-46: 187: 11.16		CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32
+	Mm
		1150515 Q155P7_MOUSE (6-848): 2.43e-28: 128: 12.29		NDE1_MOUSE (3-345): 7.37e-47: 164: 54.31
+	Hs
		772647 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92
+	Hs
		157020 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32
+	Hs
		772644 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57
+	Hs
		772645 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		MYH10_HUMAN (2-228): 6.19e-23: 102: 18.06
+	Hs
		772855 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		CYTSA_HUMAN (2-331): 7.4e-23: 102: 16.06
+	Hs
		157781 AKAP9_HUMAN (1201-3083): 1.68e-32: 142: 9.38		CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32
+	Hs
		556902 MYH7_HUMAN (2316-3114): 4.47e-31: 137: 13.33		MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57
+	Hs
		772878 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		MYH14_HUMAN (2-216): 1.79e-13: 73.5: 19.54
+	Hs
		157401 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32
+	Hs
		772814 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57
+	Hs
		1143246 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		KIFC1_HUMAN (12-245): 7.03e-23: 101: 16.24
+	Hs
		1143211 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		CTTB2_HUMAN (1-342): 7.6e-11: 65.4: 13.50