HitPredict

Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 651 Hs			1 244
+	Hs
		889230 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RND2_HUMAN (20-244): 3.92e-103: 300: 64.00
+	Hs
		889317 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RND1_HUMAN (1-244): 2.92e-100: 293: 58.20
+	Hs
		466154 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOC_HUMAN (22-213): 1.28e-92: 272: 49.48
+	Hs
		889250 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOB_HUMAN (22-200): 1.74e-90: 266: 50.84
+	Hs
		889252 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RAC1_HUMAN (24-210): 3.64e-80: 240: 43.32
+	Hs
		580933 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RAC2_HUMAN (24-211): 1.45e-76: 231: 39.89
+	Hs
		889239 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RAC3_HUMAN (24-198): 2.29e-76: 230: 44.00
+	Hs
		889257 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOG_HUMAN (23-208): 1.41e-74: 226: 42.47
+	Hs
		889242 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOA_HUMAN (25-207): 2.59e-74: 225: 50.27
+	Hs
		126507 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18
+	Hs
		889343 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		601212 NUMB_HUMAN (1-651): 9.05e-105: 333: 100.00		RHOQ_HUMAN (25-212): 8.67e-51: 166: 42.02
+	Mm
		1296744 ANS1B_MOUSE (7-213): 4.91e-49: 187: 18.75		RAB1B_MOUSE (16-242): 1.06e-76: 232: 21.49
+	Hs
		962216 ANS1B_HUMAN (7-215): 1.57e-51: 194: 19.05		RHOA_HUMAN (25-207): 2.59e-74: 225: 50.27
+	Mm
		953792 ANS1B_MOUSE (7-213): 4.91e-49: 187: 18.75		RAC3_MOUSE (24-198): 2.29e-76: 230: 44.00
+	Hs
		988581 ANS1A_HUMAN (8-244): 2.53e-40: 160: 18.49		RAC1_HUMAN (24-210): 3.64e-80: 240: 43.32
+	Hs
		953599 ANS1A_HUMAN (8-244): 2.53e-40: 160: 18.49		RAC3_HUMAN (24-198): 2.29e-76: 230: 44.00
+	Hs
		1438283 NUMBL_HUMAN (1-651): 3.42e-48: 180: 45.55		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		601525 NUMBL_HUMAN (1-651): 3.42e-48: 180: 45.55		RHOQ_HUMAN (25-212): 8.67e-51: 166: 42.02
+	Hs
		269737 CAPON_HUMAN (8-286): 6.36e-36: 143: 17.11		RHOQ_HUMAN (25-212): 8.67e-51: 166: 42.02