HitPredict

Interactor 1: KR108 (P60410)
Keratin-associated protein 10-8 (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8)
Gene: KRTAP10-8

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 259 Hs			1 236
+	Hs
		484590 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		889817 KR109_HUMAN (91-259): 1.24e-24: 101: 46.67		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		254212 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		SLIT1_HUMAN (68-230): 2.49e-09: 58.9: 17.96
+	Hs
		889943 KR10B_HUMAN (2-223): 2.24e-22: 95.2: 27.48		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		889082 KR105_HUMAN (81-259): 4.61e-22: 93.7: 45.25		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		1189429 KR411_HUMAN (62-259): 2.23e-22: 92.9: 30.35		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		1189415 KR412_HUMAN (46-259): 1.02e-19: 86: 30.56		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		1189430 KRA47_HUMAN (90-245): 1.14e-16: 76.7: 36.54		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		1189432 KRA44_HUMAN (92-250): 6.02e-16: 74.8: 33.53		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		887741 KR10A_HUMAN (3-181): 1.66e-14: 72.9: 27.96		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Dm
		1375758 TENA_DROME (47-259): 2.75e-19: 89.1: 12.61		TENA_DROME (93-236): 2.87e-21: 93.9: 21.80
+	Hs
		484591 KR109_HUMAN (91-259): 1.24e-24: 101: 46.67		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		484589 KR105_HUMAN (81-259): 4.61e-22: 93.7: 45.25		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Dm
		247258 TENA_DROME (47-259): 2.75e-19: 89.1: 12.61		TENM_DROME (2-124): 1.24e-14: 74.7: 17.71
+	Hs
		484703 KR411_HUMAN (62-259): 2.23e-22: 92.9: 30.35		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Dm
		247183 TENM_DROME (104-256): 2.05e-14: 74.8: 15.64		Q9VTP0_DROME (1-105): 1.07e-15: 77.8: 33.05
+	Dm
		246701 TENM_DROME (104-256): 2.05e-14: 74.8: 15.64		TENM_DROME (2-124): 1.24e-14: 74.7: 17.71
+	Hs
		484705 KRA44_HUMAN (92-250): 6.02e-16: 74.8: 33.53		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		484586 KR10A_HUMAN (3-181): 1.66e-14: 72.9: 27.96		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95