HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 559
+	Hs
		889400 CLK1_HUMAN (1-484): 2.4e-143: 422: 53.31		ENL_HUMAN (1-559): 1.83e-78: 259: 100.00
+	Hs
		889712 CLK3_HUMAN (1-499): 4.5e-133: 395: 59.32		ENL_HUMAN (1-559): 1.83e-78: 259: 100.00
+	Hs
		839884 DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50		AF9_HUMAN (1-559): 3.63e-75: 250: 52.36
+	Hs
		668068 CDK2_HUMAN (160-488): 2.04e-132: 387: 24.70		YETS2_HUMAN (3-502): 5.26e-36: 146: 12.96
+	Hs
		667809 CDK2_HUMAN (160-488): 2.04e-132: 387: 24.70		EP300_HUMAN (36-507): 8.6e-31: 130: 10.54
+	Hs
		667957 CDK2_HUMAN (160-488): 2.04e-132: 387: 24.70		CBP_HUMAN (36-507): 1.13e-27: 120: 11.67
+	Ce
		1170265 MBK2_CAEEL (145-487): 7.28e-111: 348: 27.93		Q21501_CAEEL (7-147): 1.19e-42: 153: 25.85
+	Hs
		1067873 DYR1B_HUMAN (108-488): 3.01e-110: 341: 29.03		EP300_HUMAN (36-507): 8.6e-31: 130: 10.54
+	Hs
		443336 CDK1_HUMAN (160-483): 1.01e-113: 339: 24.10		EP300_HUMAN (36-507): 8.6e-31: 130: 10.54
+	Hs
		1067301 DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50		EP300_HUMAN (36-507): 8.6e-31: 130: 10.54
+	Hs
		1368537 DYR1B_HUMAN (108-488): 3.01e-110: 341: 29.03		CBP_HUMAN (36-507): 1.13e-27: 120: 11.67
+	Hs
		1115870 DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50		CBP_HUMAN (36-507): 1.13e-27: 120: 11.67
+	Hs
		1116183 DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50		PCLO_HUMAN (156-526): 3.35e-09: 62.1: 10.13