HitPredict

Interactor 1: CLK3 (P49761)
Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)
Gene: CLK3

Interactor 2: RMXL1 (Q96E39)
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1)
Gene: RBMXL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 490 Hs			1 390
+	Hs
		794410 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		RBMX_HUMAN (1-366): 1.6e-43: 157: 92.10
+	Hs
		515832 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		RBY1A_HUMAN (1-363): 1.86e-32: 129: 48.53
+	Hs
		794409 CLK1_HUMAN (1-477): 3.55e-139: 410: 49.28		RBMX_HUMAN (1-366): 1.6e-43: 157: 92.10
+	Hs
		889739 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		RBY1F_HUMAN (1-363): 3.21e-32: 128: 48.27
+	Hs
		889634 CLK2_HUMAN (1-490): 5.87e-137: 405: 58.12		RMXL1_HUMAN (1-357): 1.09e-41: 152: 100.00
+	Hs
		889426 CLK1_HUMAN (1-477): 3.55e-139: 410: 49.28		SAFB1_HUMAN (7-390): 4.15e-31: 127: 14.25
+	Hs
		889686 CLK2_HUMAN (1-490): 5.87e-137: 405: 58.12		RBM7_HUMAN (2-268): 1.58e-33: 127: 22.68
+	Hs
		889723 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		PABP4_HUMAN (8-97): 6.63e-19: 90.7: 30.00
+	Hs
		550182 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		PABP1_HUMAN (8-97): 2.65e-17: 85.7: 28.89
+	Hs
		668090 CDK2_HUMAN (153-483): 7.53e-136: 395: 24.26		RBM7_HUMAN (2-268): 1.58e-33: 127: 22.68
+	Hs
		889731 CLK3_HUMAN (1-490): 4.11e-150: 439: 100.00		RBM39_HUMAN (3-112): 1.32e-14: 77.2: 22.73
+	Hs
		794477 DYR1A_HUMAN (33-485): 2.69e-113: 353: 26.21		RBMX_HUMAN (1-366): 1.6e-43: 157: 92.10
+	Hs
		550181 CLK2_HUMAN (1-490): 5.87e-137: 405: 58.12		PABP1_HUMAN (8-97): 2.65e-17: 85.7: 28.89
+	Hs
		889422 CLK1_HUMAN (1-477): 3.55e-139: 410: 49.28		RBM39_HUMAN (3-112): 1.32e-14: 77.2: 22.73
+	Hs
		889567 CLK2_HUMAN (1-490): 5.87e-137: 405: 58.12		RBM39_HUMAN (3-112): 1.32e-14: 77.2: 22.73
+	Hs
		550125 CDK2_HUMAN (153-483): 7.53e-136: 395: 24.26		PABP1_HUMAN (8-97): 2.65e-17: 85.7: 28.89
+	Hs
		1115639 DYR1A_HUMAN (33-485): 2.69e-113: 353: 26.21		CIRBP_HUMAN (4-145): 3.74e-32: 120: 45.70
+	Hs
		667773 CDK2_HUMAN (153-483): 7.53e-136: 395: 24.26		RBM3_HUMAN (8-88): 1.06e-15: 75.9: 55.56
+	Hs
		1101947 DYR1A_HUMAN (33-485): 2.69e-113: 353: 26.21		PABP4_HUMAN (8-97): 6.63e-19: 90.7: 30.00
+	Hs
		550275 DYR1A_HUMAN (33-485): 2.69e-113: 353: 26.21		PABP1_HUMAN (8-97): 2.65e-17: 85.7: 28.89