Interactor 1: DOA (P49762)
Serine/threonine-protein kinase Doa (EC 2.7.12.1) (Protein darkener of apricot)
Gene: DOA
Interactor 2: CDK8 (Q9VT57)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (DmCdk8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8)
Gene: CDK8
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29606597 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0106310 - protein serine kinase activity |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025