HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	19492042
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 345
+	Hs
		564564 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		148653 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		724757 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Mm
		823530 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		CTRO_MOUSE (12-211): 7.2e-23: 102: 19.32
+	Hs
		724776 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		1137905 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		148608 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		725125 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Mm
		823529 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		CTRO_MOUSE (12-211): 7.2e-23: 102: 19.32
+	Rn
		92842 RHOA_RAT (5-191): 9.99e-82: 242: 53.48		CTRO_RAT (12-211): 2.42e-23: 103: 19.32
+	Hs
		725138 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Mm
		823539 RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48		CTRO_MOUSE (12-211): 7.2e-23: 102: 19.32
+	Hs
		925344 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		894116 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		951069 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		900570 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		545430 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		MRCKA_HUMAN (2-204): 1.99e-20: 94.7: 17.41
+	Hs
		564571 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKG_HUMAN (11-286): 7.32e-09: 59.3: 11.42
+	Hs
		925356 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKG_HUMAN (11-286): 7.32e-09: 59.3: 11.42
+	Hs
		894128 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MRCKG_HUMAN (11-286): 7.32e-09: 59.3: 11.42