HitPredict

Interactor 1: MXI1 (P50540)
Max-interacting protein 1 (Max interactor 1)
Gene: MXI1

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	7889570
Identification Methods	coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 228 Mm			1 1098
+	Hs
		274297 MXI1_HUMAN (1-228): 7.97e-92: 270: 96.05		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Mm
		896181 MAD1_MOUSE (7-223): 1.21e-65: 204: 55.56		SIN3B_MOUSE (1-1098): 0: 1367: 100.00
+	Mm
		148318 MNT_MOUSE (42-184): 2.47e-40: 147: 30.57		SIN3B_MOUSE (1-1098): 0: 1367: 100.00
+	Hs
		274274 MYC_HUMAN (27-150): 7e-38: 138: 28.03		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Rn
		64501 MYC_RAT (27-150): 9.4e-39: 141: 28.03		A6K9M6_RAT (1-280): 2.58e-95: 306: 96.79
+	Hs
		896207 MXI1_HUMAN (1-228): 7.97e-92: 270: 96.05		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49
+	Mm
		896217 MXI1_MOUSE (1-228): 4.58e-88: 261: 100.00		SIN3A_MOUSE (71-357): 1.14e-12: 74.9: 14.49
+	Mm
		896180 MAD1_MOUSE (7-223): 1.21e-65: 204: 55.56		SIN3A_MOUSE (71-357): 1.14e-12: 74.9: 14.49
+	Hs
		1050746 MAD1_HUMAN (7-223): 4.86e-62: 195: 58.07		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49
+	Mm
		1221137 Q91VN7_MOUSE (21-217): 7.98e-56: 178: 53.03		SIN3A_MOUSE (71-357): 1.14e-12: 74.9: 14.49
+	Dm
		1216762 X2JDM5_DROME (32-153): 1.26e-34: 132: 26.83		Q5U0Y0_DROME (134-264): 5.02e-23: 108: 41.79
+	Hs
		1403010 MAD3_HUMAN (8-193): 3.07e-49: 161: 49.47		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49
+	Mm
		148317 MNT_MOUSE (42-184): 2.47e-40: 147: 30.57		SIN3A_MOUSE (71-357): 1.14e-12: 74.9: 14.49
+	Ce
		63504 MXL3_CAEEL (65-167): 2.45e-20: 87.6: 25.24		SIN3_CAEEL (4-156): 6.3e-31: 134: 31.82
+	Hs
		1403005 MNT_HUMAN (42-184): 1.89e-37: 139: 29.94		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49
+	Hs
		372919 MYC_HUMAN (27-150): 7e-38: 138: 28.03		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49
+	Hs
		959638 MAX_HUMAN (60-166): 2.05e-22: 91.4: 19.63		SIN3A_HUMAN (71-357): 9.6e-13: 74.9: 14.49