HitPredict

Interactor 1: M9ND00 (M9ND00)
Dynamin associated protein 160, isoform D
Gene: Dap160

Interactor 2: DYN (P27619)
Dynamin (EC 3.6.5.5) (Protein shibire) (dDyn)
Gene: shi

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	18701694, 23321638, 24977345, 9668096, 10918586, 11711432, 14622578, 26538647
Identification Methods	affinity chromatography technology, far western blotting, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0048488 - synaptic vesicle endocytosis GO:0150007 - clathrin-dependent synaptic vesicle endocytosis GO:0150008 - bulk synaptic vesicle endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1190 Dm			1 877
+	Hs
		1050684 ITSN1_HUMAN (3-1183): 8.66e-105: 366: 25.57		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Mm
		810542 ITSN1_MOUSE (3-1183): 1.77e-103: 362: 26.01		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Hs
		896763 ITSN1_HUMAN (3-1183): 8.66e-105: 366: 25.57		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		810562 ITSN1_MOUSE (3-1183): 1.77e-103: 362: 26.01		DYN2_MOUSE (1-832): 0: 1008: 67.06
+	Rn
		638964 ITSN1_RAT (3-1183): 7.26e-102: 357: 25.55		DYN1_RAT (1-844): 0: 1012: 65.52
+	Hs
		896907 ITSN2_HUMAN (1-1086): 6.65e-99: 348: 28.82		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Hs
		896912 EP15R_HUMAN (3-521): 9.24e-64: 236: 21.97		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Dm
		263714 O61618_DROME (589-1183): 4.36e-23: 108: 11.20		DYN_DROME (1-877): 0: 1132: 100.00
+	Dm
		95602 E3CTP7_DROME (373-574): 5.66e-11: 68.9: 15.84		DYN_DROME (1-877): 0: 1132: 100.00
+	Hs
		839720 EPS15_HUMAN (2-397): 2.16e-36: 151: 13.82		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		237068 NCK2_MOUSE (676-912): 2.03e-19: 93.8: 20.75		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Hs
		593970 NCK1_HUMAN (670-935): 3.43e-19: 93.1: 16.55		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Hs
		222060 NCK2_HUMAN (944-1093): 7.12e-19: 92: 20.56		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Mm
		810535 SH3K1_MOUSE (1026-1104): 9.55e-14: 78: 26.58		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Hs
		1050705 SH3K1_HUMAN (1025-1087): 9.71e-13: 74.7: 39.68		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Hs
		896808 SH3R1_HUMAN (837-1078): 3.11e-15: 83.2: 15.53		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		810555 SH3K1_MOUSE (1026-1104): 9.55e-14: 78: 26.58		DYN2_MOUSE (1-832): 0: 1008: 67.06
+	Hs
		896947 CD2AP_HUMAN (626-731): 1.47e-13: 77.3: 21.24		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Hs
		896850 SH3K1_HUMAN (1025-1087): 9.71e-13: 74.7: 39.68		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Ce
		810584 Q9U2T9_CAEEL (657-1102): 2.56e-14: 80.1: 10.38		DYN1_CAEEL (1-759): 0: 981: 68.51