HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0098793 - presynapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 864
+	Hs
		839720 DYN2_HUMAN (1-870): 0: 1057: 100.00		EPS15_HUMAN (1-862): 3.26e-109: 358: 41.50
+	Hs
		896763 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN1_HUMAN (1-556): 5.64e-32: 137: 12.77
+	Mm
		810562 DYN2_MOUSE (1-870): 0: 1057: 98.16		ITSN1_MOUSE (2-512): 2.67e-30: 131: 14.62
+	Hs
		896907 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN2_HUMAN (2-545): 6.29e-25: 114: 13.09
+	Hs
		1050684 DYN1_HUMAN (1-846): 0: 1002: 79.04		ITSN1_HUMAN (1-556): 5.64e-32: 137: 12.77
+	Mm
		810542 DYN1_MOUSE (1-844): 0: 1003: 79.23		ITSN1_MOUSE (2-512): 2.67e-30: 131: 14.62
+	Rn
		638964 DYN1_RAT (1-846): 0: 994: 78.57		ITSN1_RAT (18-512): 8.96e-29: 126: 14.49
+	Mm
		749842 DYN1_MOUSE (1-844): 0: 1003: 79.23		KIF5A_MOUSE (204-821): 8.65e-20: 97: 7.85
+	Dm
		95602 DYN_DROME (6-842): 0: 928: 66.23		E3CTP7_DROME (504-807): 1.23e-13: 77: 11.90
+	Dm
		118279 DYN_DROME (6-842): 0: 928: 66.23		M9ND00_DROME (3-120): 2.13e-13: 76.6: 22.03
+	Dm
		263714 DYN_DROME (6-842): 0: 928: 66.23		O61618_DROME (3-120): 1e-12: 74.3: 22.03
+	Ce
		810584 DYN1_CAEEL (3-823): 0: 899: 61.86		Q9U2T9_CAEEL (1-434): 2.18e-12: 73.1: 10.12