HitPredict

Interactor 1: O61618 (O61618)
Dynamin associated protein isoform Dap160-1
Gene: Dap160

Interactor 2: DYN (P27619)
Dynamin (EC 3.6.5.5) (Protein shibire) (dDyn)
Gene: shi

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0048488 - synaptic vesicle endocytosis GO:0150007 - clathrin-dependent synaptic vesicle endocytosis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1094 Dm			1 877
+	Dm
		118279 M9ND00_DROME (1-1094): 3.09e-172: 539: 98.18		DYN_DROME (1-877): 0: 1132: 100.00
+	Mm
		810542 ITSN1_MOUSE (3-1093): 8.67e-105: 364: 27.24		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Mm
		810562 ITSN1_MOUSE (3-1093): 8.67e-105: 364: 27.24		DYN2_MOUSE (1-832): 0: 1008: 67.06
+	Rn
		638964 ITSN1_RAT (3-1093): 4.51e-103: 359: 26.58		DYN1_RAT (1-844): 0: 1012: 65.52
+	Hs
		896912 EP15R_HUMAN (3-483): 1.25e-61: 228: 21.74		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Dm
		95602 E3CTP7_DROME (10-678): 1.92e-20: 99.5: 14.41		DYN_DROME (1-877): 0: 1132: 100.00
+	Hs
		1050684 ITSN1_HUMAN (81-1086): 3.75e-51: 200: 15.29		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Hs
		896763 ITSN1_HUMAN (81-1086): 3.75e-51: 200: 15.29		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		237068 NCK2_MOUSE (680-936): 1.05e-20: 97.4: 18.15		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Hs
		593970 NCK1_HUMAN (681-936): 2.45e-20: 96.3: 16.67		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Hs
		839720 EPS15_HUMAN (8-387): 1.52e-20: 100: 14.84		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Hs
		896780 SH319_HUMAN (815-1090): 1.27e-18: 93.7: 14.44		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		810535 SH3K1_MOUSE (874-1024): 5.17e-12: 72.4: 22.73		DYN1_MOUSE (1-838): 0: 1020: 65.74
+	Hs
		896907 ITSN2_HUMAN (596-1090): 2.03e-15: 83.7: 10.26		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Hs
		1050705 SH3K1_HUMAN (677-964): 4.1e-11: 69.1: 14.24		DYN1_HUMAN (1-844): 0: 1018: 65.52
+	Hs
		896947 CD2AP_HUMAN (642-735): 3.52e-13: 75.8: 22.45		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Mm
		810555 SH3K1_MOUSE (874-1024): 5.17e-12: 72.4: 22.73		DYN2_MOUSE (1-832): 0: 1008: 67.06
+	Hs
		896850 SH3K1_HUMAN (677-964): 4.1e-11: 69.1: 14.24		DYN2_HUMAN (1-849): 0: 1005: 65.06
+	Ce
		810584 Q9U2T9_CAEEL (505-1094): 3.24e-11: 69.8: 9.31		DYN1_CAEEL (1-759): 0: 981: 68.51