HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: UBAP2 (Q5T6F2)
Ubiquitin-associated protein 2 (UBAP-2) (RNA polymerase II degradation factor UBAP2)
Gene: UBAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1119
+	Hs
		903219 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		UBP2L_HUMAN (1-1119): 1.83e-54: 209: 39.07
+	Mm
		903669 WDR5_MOUSE (1-334): 2.77e-131: 379: 100.00		KMT2C_MOUSE (297-1108): 1.01e-17: 91.8: 12.34
+	Hs
		903374 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2C_HUMAN (178-889): 3.43e-14: 80: 9.69
+	Hs
		152622 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2D_HUMAN (223-1040): 1.49e-09: 64.7: 8.49
+	Hs
		209436 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		MDC1_HUMAN (167-842): 7.33e-12: 72.3: 10.62
+	Dm
		1370295 POC1_DROME (11-254): 9.16e-70: 224: 25.82		Q9VLS7_DROME (185-1113): 1.35e-21: 104: 9.45
+	Hs
		1049862 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		UBP2L_HUMAN (1-1119): 1.83e-54: 209: 39.07
+	Hs
		152663 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		KMT2D_HUMAN (223-1040): 1.49e-09: 64.7: 8.49
+	Dm
		1370339 FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10		Q9VLS7_DROME (185-1113): 1.35e-21: 104: 9.45
+	Hs
		72754 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		B4DET5_HUMAN (174-995): 4.84e-27: 120: 9.56
+	Hs
		152678 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		KMT2D_HUMAN (223-1040): 1.49e-09: 64.7: 8.49
+	Hs
		1281391 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PRR36_HUMAN (679-1117): 7.5e-09: 62.4: 12.92
+	Hs
		1056932 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MDC1_HUMAN (167-842): 7.33e-12: 72.3: 10.62