HitPredict

Interactor 1: CHD4 (Q6PDQ2)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.-)
Gene: CHD4

Interactor 2: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~Chromo, Chromo~PHD, Chromo~SNF2-rel_dom
Common GO terms	GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1915 Mm			1 183
+	Hs
		1097298 CHD4_HUMAN (1-1915): 0: 1662: 97.76		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853260 CHD4_HUMAN (1-1915): 0: 1662: 97.76		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Mm
		1014260 CHD4_MOUSE (1-1903): 0: 1664: 100.00		CBX1_MOUSE (36-180): 1.03e-53: 170: 71.33
+	Hs
		1014099 CHD4_HUMAN (1-1915): 0: 1662: 97.76		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		216438 CHD4_HUMAN (1-1915): 0: 1662: 97.76		SUV91_HUMAN (3-179): 4.75e-40: 141: 16.20
+	Hs
		1088313 CHD3_HUMAN (19-1908): 0: 1582: 67.77		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097444 CHD5_HUMAN (79-1912): 0: 1558: 70.43		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853240 CHD3_HUMAN (19-1908): 0: 1582: 67.77		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		1014079 CHD3_HUMAN (19-1908): 0: 1582: 67.77		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		129726 CHD3_HUMAN (19-1908): 0: 1582: 67.77		CBX4_HUMAN (21-121): 4.97e-27: 108: 29.52
+	Hs
		1097601 CHD7_HUMAN (4-1734): 0: 795: 21.61		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		703310 SMCA1_HUMAN (609-1605): 0: 780: 27.77		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		243620 SMCA5_HUMAN (596-1580): 0: 766: 26.91		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097577 CHD8_HUMAN (7-1734): 0: 753: 22.46		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		703292 SMCA1_HUMAN (609-1605): 0: 780: 27.77		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		1097323 CHD9_HUMAN (490-1697): 0: 729: 27.56		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		160079 CHD1_HUMAN (526-1726): 0: 700: 29.22		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Dm
		426660 ISWI_DROME (614-1625): 0: 754: 26.44		HP1_DROME (9-180): 2.13e-45: 150: 38.73
+	Hs
		129816 CHD7_HUMAN (4-1734): 0: 795: 21.61		CBX4_HUMAN (21-121): 4.97e-27: 108: 29.52
+	Hs
		853328 CHD1L_HUMAN (715-1225): 4.85e-118: 399: 44.04		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89