HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	27705803, 33022573
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 543
+	Hs
		826601 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821152 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573201 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1306650 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		792942 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		1202777 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826784 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826854 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821326 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821390 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573384 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573451 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826748 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573346 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821437 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		843139 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843299 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843361 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843273 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843219 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79