HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SH3R3 (Q8TEJ3)
E3 ubiquitin-protein ligase SH3RF3 (EC 2.3.2.27) (Plenty of SH3s 2) (SH3 domain-containing RING finger protein 3) (SH3 multiple domains protein 4)
Gene: SH3RF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.604

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 882
+	Hs
		909744 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH3R1_HUMAN (46-882): 1.03e-98: 330: 42.17
+	Mm
		910242 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SRBS2_MOUSE (286-882): 2.2e-22: 105: 12.62
+	Hs
		909656 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SPD2A_HUMAN (59-881): 2.54e-21: 102: 10.28
+	Mm
		292560 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SPD2A_MOUSE (110-881): 2.78e-20: 99.1: 8.87
+	Hs
		904687 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SPD2A_HUMAN (59-881): 2.54e-21: 102: 10.28
+	Hs
		298967 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS2_HUMAN (523-882): 1.7e-18: 93.2: 14.79
+	Hs
		299007 V9HW98_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS2_HUMAN (523-882): 1.7e-18: 93.2: 14.79
+	Hs
		904578 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARHG6_HUMAN (769-882): 3.47e-19: 94.9: 19.30
+	Hs
		298965 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRBS2_HUMAN (523-882): 1.7e-18: 93.2: 14.79
+	Hs
		275184 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GRAP2_HUMAN (816-882): 9.26e-17: 84.5: 19.40
+	Hs
		909551 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ARHG7_HUMAN (829-882): 7.71e-16: 84.1: 37.04
+	Hs
		909849 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH3R3_HUMAN (674-882): 7.95e-15: 81: 19.62
+	Hs
		904551 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARHG7_HUMAN (829-882): 7.71e-16: 84.1: 37.04
+	Hs
		909634 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH319_HUMAN (166-251): 5.64e-14: 78.1: 29.07
+	Hs
		909544 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SPTN1_HUMAN (652-882): 1.46e-12: 74.1: 13.79
+	Hs
		904655 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SH319_HUMAN (166-251): 5.64e-14: 78.1: 29.07
+	Hs
		904543 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SPTN1_HUMAN (652-882): 1.46e-12: 74.1: 13.79
+	Hs
		909706 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DNMBP_HUMAN (666-881): 2.63e-10: 66.6: 10.22
+	Hs
		909979 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS1_HUMAN (122-250): 1.3e-09: 64.4: 20.61
+	Hs
		904742 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DNMBP_HUMAN (666-881): 2.63e-10: 66.6: 10.22