Protein: ARHGJ
Rho guanine nucleotide exchange factor 19 (Ephexin-2)

Gene: ARHGJ, ARHGEF19
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q8IW93

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0032956 - regulation of actin cytoskeleton organization
GO:0042060 - wound healing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

962242

RHOA
Transforming protein RhoA

2

20

Small-scale

0.768

High

1279844

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

2

12

High-throughput

0.737

High

159373

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

16

Small-scale

0.618

High

988506

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.618

High

1309679

PAK5
Serine/threonine-protein kinase PAK 5

2

8

High-throughput

0.606

High

915994

NUP98
Nuclear pore complex protein Nup98-Nup96

2

5

High-throughput

0.571

High

971748

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.571

High

1309664

RN169
E3 ubiquitin-protein ligase RNF169

2

7

High-throughput

0.571

High

1309666

NUP35
Nucleoporin NUP35

2

2

High-throughput

0.571

High

1309682

TPX2
Targeting protein for Xklp2

2

4

High-throughput

0.571

High

1309685

WBP11
WW domain-binding protein 11

2

3

High-throughput

0.571

High

192608

NUP42
Nucleoporin NUP42

2

0

High-throughput

0.547

High

192834

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

0

High-throughput

0.547

High

851606

GATA4
Transcription factor GATA-4

2

0

High-throughput

0.547

High

1309671

CDCA5
Sororin

2

0

High-throughput

0.547

High

1309673

UIF
UAP56-interacting factor

2

0

High-throughput

0.547

High

1309677

TLS1
Splicing factor C9orf78

2

0

High-throughput

0.547

High

298533

SPF30
Survival of motor neuron-related-splicing factor 30

2

3

High-throughput

0.521

High

352180

MBD3
Methyl-CpG-binding domain protein 3

2

2

High-throughput

0.521

High

424430

HMGN1
Non-histone chromosomal protein HMG-14

2

4

High-throughput

0.521

High

876608

NEST
Nestin

2

20

High-throughput

0.521

High

940403

MAZ
Myc-associated zinc finger protein

2

2

High-throughput

0.521

High

1013082

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

2

2

High-throughput

0.521

High

1150758

SF01
Splicing factor 1

2

7

High-throughput

0.521

High

1168529

KNOP1
Lysine-rich nucleolar protein 1

2

1

High-throughput

0.521

High

1210479

HP1B3
Heterochromatin protein 1-binding protein 3

2

2

High-throughput

0.521

High

1211565

ZN362
Zinc finger protein 362

2

1

High-throughput

0.521

High

1245385

ZC3HE
Zinc finger CCCH domain-containing protein 14

2

1

High-throughput

0.521

High

1247266

WDR74
WD repeat-containing protein 74

2

12

High-throughput

0.521

High

1309355

ARI3B
AT-rich interactive domain-containing protein 3B

2

1

High-throughput

0.521

High

1309665

SRFB1
Serum response factor-binding protein 1

2

2

High-throughput

0.521

High

1309668

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

5

High-throughput

0.521

High

1309674

EBP2
Probable rRNA-processing protein EBP2

2

1

High-throughput

0.521

High

1309675

CCD86
Coiled-coil domain-containing protein 86

2

5

High-throughput

0.521

High

1309676

RBM22
Pre-mRNA-splicing factor RBM22

2

7

High-throughput

0.521

High

1309678

CWC15
Spliceosome-associated protein CWC15 homolog

2

1

High-throughput

0.521

High

1309680

NUP50
Nuclear pore complex protein Nup50

2

1

High-throughput

0.521

High

1309681

ZN346
Zinc finger protein 346

2

2

High-throughput

0.521

High

1309683

UTP16
U3 small nucleolar RNA-associated protein NOL7

2

3

High-throughput

0.521

High

1309684

KLH20
Kelch-like protein 20

1

5

Small-scale

0.481

High

451203

NFL
Neurofilament light polypeptide

1

19

High-throughput

0.479

High

483143

CLCA
Clathrin light chain A

1

5

High-throughput

0.479

High

904904

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

1156138

ZYX
Zyxin

1

5

High-throughput

0.479

High

1309686

DAAM1
Disheveled-associated activator of morphogenesis 1

1

3

Small-scale

0.479

High

161056

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

7

Small-scale

0.457

High

1157227

AINX
Alpha-internexin

1

18

High-throughput

0.437

High

1309672

FUBP3
Far upstream element-binding protein 3

1

13

High-throughput

0.437

High

1139953

RRS1
Ribosome biogenesis regulatory protein homolog

2

0

High-throughput

0.298

High

1245458

CC137
Coiled-coil domain-containing protein 137

2

0

High-throughput

0.298

High

1280011

CE024
UPF0461 protein C5orf24

2

0

High-throughput

0.298

High

1295259

P66A
Transcriptional repressor p66-alpha

2

0

High-throughput

0.298

High

1309663

ZCHC9
Zinc finger CCHC domain-containing protein 9

2

0

High-throughput

0.298

High

1309667

CCD12
Coiled-coil domain-containing protein 12

2

0

High-throughput

0.298

High

1309669

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

2

0

High-throughput

0.298

High

1309670

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.298

High


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Last updated: 11Aug2025