HitPredict

Interactor 1: UB2G1 (P62253)
Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
Gene: UBE2G1

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 19560420, 22101235, 25451919, 31061093, 21209460, 12847084, 19661182
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains G2BR~UQ_con, UQ_con~zf-RING_2
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0070936 - protein K48-linked ubiquitination
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 170
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024