HitPredict

Interactor 1: AFF3 (P51826)
AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4)
Gene: AFF3

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 1834
+	Hs
		1314469 AFF4_HUMAN (22-1225): 3.83e-72: 265: 31.84		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		1235650 NIPBL_HUMAN (24-1005): 2.33e-60: 230: 9.73		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		1129646 MDC1_HUMAN (78-923): 2.09e-27: 123: 10.07		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		854111 NIPBL_HUMAN (24-1005): 2.33e-60: 230: 9.73		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		590235 MUC1_HUMAN (188-1152): 1.43e-57: 220: 9.63		MUC1_HUMAN (870-1755): 3.14e-23: 110: 10.32
+	Hs
		854056 MDC1_HUMAN (78-923): 2.09e-27: 123: 10.07		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1403962 MUC4_HUMAN (210-1159): 5.92e-14: 79.3: 8.09		MUC4_HUMAN (850-1813): 9.84e-34: 145: 10.42
+	Hs
		1129588 MDC1_HUMAN (78-923): 2.09e-27: 123: 10.07		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		161491 KMT2C_HUMAN (22-983): 4.41e-35: 148: 9.41		KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52
+	Hs
		1129637 MDC1_HUMAN (78-923): 2.09e-27: 123: 10.07		MICA3_HUMAN (1139-1747): 8.47e-13: 76.3: 10.24
+	Dm
		119660 M9PB30_DROME (32-481): 1.13e-10: 68.9: 8.65		M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28
+	Hs
		861240 PRG4_HUMAN (32-728): 1.01e-22: 107: 9.18		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		161429 KMT2D_HUMAN (341-979): 3.05e-09: 63.9: 10.28		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Mm
		1455913 PCLO_MOUSE (690-1157): 4.27e-11: 70.1: 8.32		PCLO_MOUSE (836-1825): 7.2e-16: 86.7: 10.09
+	Hs
		861124 ANK2_HUMAN (289-1002): 3.35e-11: 70.2: 9.44		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90