HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 392
+	Hs
		919912 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		849492 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		895959 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		895947 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Dm
		218245 UBCD1_DROME (7-150): 3.09e-72: 216: 29.73		O44382_DROME (31-154): 3.56e-29: 120: 25.56
+	Hs
		921784 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		919704 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		903084 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		849304 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		895772 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		908310 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53
+	Hs
		908940 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62