HitPredict

Interactor 1: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0071011 - precatalytic spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 119 Hs			1 401
+	Hs
		911933 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SPF45_HUMAN (1-401): 4.66e-158: 452: 100.00
+	Hs
		912293 SMD1_HUMAN (1-96): 1.18e-34: 117: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054708 LSM4_HUMAN (1-89): 1.24e-33: 115: 23.33		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054694 LSM2_HUMAN (1-88): 7.62e-33: 111: 31.11		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		912633 SMD3_HUMAN (2-102): 1.06e-31: 110: 28.71		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		911835 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641701 SMD1_HUMAN (1-96): 1.18e-34: 117: 100.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		911991 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		212121 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		HTSF1_HUMAN (305-388): 4.02e-17: 85.4: 27.78