HitPredict

Interactor 1: UBCD4 (P52486)
Ubiquitin-conjugating enzyme E2-22 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: Ubc4

Interactor 2: Q9VXP1 (Q9VXP1)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: sordd1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	37061542, 14605208, unassigned1513
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 199 Dm			1 277
+	Dm
		912356 UBCD4_DROME (1-199): 1.99e-78: 234: 100.00		Q8IR26_DROME (1-276): 2.54e-72: 225: 91.70
+	Xl
		1220172 Q8AVM8_XENLA (1-199): 1.13e-77: 232: 68.84		Q5XGX4_XENLA (91-277): 1.92e-55: 179: 54.01
+	Hs
		957646 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RN185_HUMAN (89-277): 1.05e-51: 169: 53.16
+	Hs
		1391936 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RN185_HUMAN (89-277): 1.05e-51: 169: 53.16
+	Dm
		912355 UBCD4_DROME (1-199): 1.99e-78: 234: 100.00		Q8IQM1_DROME (108-276): 3.93e-47: 156: 48.52
+	Hs
		957657 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RNF5_HUMAN (103-241): 2.1e-40: 140: 55.40
+	Hs
		1408213 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RNF5_HUMAN (103-241): 2.1e-40: 140: 55.40
+	At
		762771 UBC9_ARATH (4-155): 7.17e-76: 226: 41.45		Q9LN67_ARATH (123-210): 1.18e-32: 121: 51.06
+	Hs
		957675 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		TRI39_HUMAN (122-247): 3.98e-28: 114: 17.32
+	Hs
		957662 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		TRI31_HUMAN (116-254): 2.59e-27: 111: 20.57
+	Hs
		957664 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		TRIM5_HUMAN (120-236): 5.39e-27: 111: 18.33
+	Hs
		1439327 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		TRI39_HUMAN (122-247): 3.98e-28: 114: 17.32
+	Hs
		1420388 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		TRI31_HUMAN (116-254): 2.59e-27: 111: 20.57
+	Hs
		1420579 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		TRIM5_HUMAN (120-236): 5.39e-27: 111: 18.33
+	Hs
		623249 UB2D2_HUMAN (4-154): 5.95e-76: 226: 41.72		RO52_HUMAN (119-262): 5.42e-28: 113: 18.62
+	Hs
		957592 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RNF4_HUMAN (3-178): 1.2e-26: 104: 17.49
+	Mm
		982385 UB2D2_MOUSE (4-154): 5.95e-76: 226: 41.72		TRI17_MOUSE (111-241): 2.89e-27: 111: 16.43
+	Hs
		1005268 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RNF4_HUMAN (3-178): 1.2e-26: 104: 17.49
+	Hs
		798918 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		BRCA1_HUMAN (124-174): 2.42e-16: 80.7: 35.29
+	Hs
		798955 UB2D2_HUMAN (4-154): 5.95e-76: 226: 41.72		BRCA1_HUMAN (124-174): 2.42e-16: 80.7: 35.29