Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 30021884, 34349018, 37071682, 20953179, 20498094
Identification Methods proximity labelling technology, cross-linking study, biochemical, affinity chromatography technology, dynamic light scattering, molecular sieving
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~Histone
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 103
Hs

1 136
+ Hs
+ Mm
+ Xl
+ Hs
+ Mm
+ Xl
+ Hs
+ Mm
+ Ce
+ Hs
+ Sp
+ Hs
+ Sc
+ Ce
+ Hs
+ Kl
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024