HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: LRC46 (Q96FV0)
Leucine-rich repeat-containing protein 46
Gene: LRRC46

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_8~Pkinase
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 321
+	Hs
		920078 PLK1_HUMAN (1-603): 0: 619: 100.00		CNTRL_HUMAN (20-223): 7.66e-35: 136: 22.97
+	Hs
		920096 PLK1_HUMAN (1-603): 0: 619: 100.00		CEP97_HUMAN (82-204): 1.17e-09: 61.3: 26.40
+	At
		1057417 CDPK1_ARATH (1-498): 8.16e-155: 459: 22.09		CLV1_ARATH (8-299): 2.1e-28: 117: 9.90
+	Hs
		1146495 KS6A2_HUMAN (1-367): 7.46e-105: 334: 22.43		NISCH_HUMAN (11-316): 2.84e-39: 149: 18.15
+	Hs
		1122237 KS6A1_HUMAN (1-362): 1.66e-108: 344: 24.87		SCRIB_HUMAN (77-302): 2.29e-21: 96.9: 14.41
+	Hs
		1122234 KS6A2_HUMAN (1-367): 7.46e-105: 334: 22.43		SCRIB_HUMAN (77-302): 2.29e-21: 96.9: 14.41
+	Hs
		908111 KS6A3_HUMAN (1-326): 4.97e-103: 329: 25.44		SCRIB_HUMAN (77-302): 2.29e-21: 96.9: 14.41
+	Hs
		170216 AURKA_HUMAN (28-307): 4.41e-43: 160: 32.17		CNTRL_HUMAN (20-223): 7.66e-35: 136: 22.97
+	Dm
		356685 PLK4_DROME (58-304): 7.65e-56: 203: 41.04		Q9VQV7_DROME (25-162): 1.3e-14: 76.4: 26.81
+	Sc
		448603 SNF1_YEAST (59-336): 1.67e-45: 172: 35.84		CYAA_YEAST (19-296): 4.83e-21: 95.8: 15.02
+	Sc
		448696 SNF1_YEAST (59-336): 1.67e-45: 172: 35.84		SDS22_YEAST (20-182): 1.16e-10: 63.7: 22.49
+	Hs
		170222 AURKA_HUMAN (28-307): 4.41e-43: 160: 32.17		CEP97_HUMAN (82-204): 1.17e-09: 61.3: 26.40