Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1
Interactor 2: DYR1B (Q9Y463)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)
Gene: DYRK1B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32707033 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
