HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.863

Property	Details
Experiments	22065575, 26895380, 23625927
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 661
+	Hs
		903521 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		WDR26_HUMAN (28-661): 5.33e-158: 471: 100.00
+	Hs
		920927 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		792949 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		LIS1_HUMAN (394-661): 1.17e-77: 255: 15.23
+	Hs
		921751 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		NLE1_HUMAN (45-428): 8.11e-31: 128: 15.25
+	Hs
		921608 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		903349 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		920988 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		903418 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		282874 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18
+	Mm
		921801 GBB2_MOUSE (1-340): 1e-105: 314: 90.29		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Mm
		921102 GBB1_MOUSE (1-340): 7.02e-105: 312: 100.00		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Hs
		903428 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		903077 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Dm
		1358845 WDS_DROME (3-215): 1.22e-57: 192: 19.55		WDS_DROME (519-661): 5.87e-42: 157: 19.58
+	Hs
		903551 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		NLE1_HUMAN (45-428): 8.11e-31: 128: 15.25
+	Hs
		1288390 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		282871 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18