Protein: UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)

Gene: UFD1
Organism: Homo sapiens
Interactions: 115
UniProt ID: Q92890

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

875181

TERA
Transitional endoplasmic reticulum ATPase

27

8

Small-scale

0.768

High

1251695

NPL4
Nuclear protein localization protein 4 homolog

15

7

Small-scale

0.759

High

476140

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

6

6

Small-scale

0.726

High

1272245

FAF1
FAS-associated factor 1

5

9

Small-scale

0.709

High

1272244

AMFR
E3 ubiquitin-protein ligase AMFR

2

1

Small-scale

0.624

High

347497

MYC
Myc proto-oncogene protein

3

0

High-throughput

0.613

High

299439

UBXN7
UBX domain-containing protein 7

2

7

High-throughput

0.611

High

1272224

FAF2
FAS-associated factor 2

2

8

High-throughput

0.611

High

791829

HD
Huntingtin

2

0

High-throughput

0.594

High

1272228

UBX10
UBX domain-containing protein 10

2

0

High-throughput

0.585

High

497388

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

1080196

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.576

High

1272223

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

2

0

Small-scale

0.576

High

1272226

VCIP1
Deubiquitinating protein VCPIP1

2

0

High-throughput

0.576

High

1115480

SV2C
Synaptic vesicle glycoprotein 2C

2

1

High-throughput

0.574

High

1272240

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1272246

NSF1C
NSFL1 cofactor p47

2

0

High-throughput

0.559

High

1272232

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

Small-scale

0.537

High

116701

UBXN8
UBX domain-containing protein 8

1

5

High-throughput

0.536

High

979335

UBXN1
UBX domain-containing protein 1

1

6

High-throughput

0.536

High

388629

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

509695

UBL4A
Ubiquitin-like protein 4A

1

5

High-throughput

0.515

High

1130400

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

Small-scale

0.513

High

643894

SYVC
Valine--tRNA ligase

1

0

High-throughput

0.513

High

893584

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.513

High

1184842

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.513

High

1272238

EKI2
Ethanolamine kinase 2

1

0

High-throughput

0.513

High

1272243

ANC2
Anaphase-promoting complex subunit 2

1

2

High-throughput

0.508

High

208855

CHM2A
Charged multivesicular body protein 2a

1

0

Small-scale

0.504

High

1272234

UBXN6
UBX domain-containing protein 6

1

1

Small-scale

0.501

High

380138

MAS
Proto-oncogene Mas

1

1

High-throughput

0.489

High

505519

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.489

High

674772

AA1R
Adenosine receptor A1

1

1

High-throughput

0.489

High

387232

P53
Cellular tumor antigen p53

1

0

High-throughput

0.486

High

436632

TNR16
Tumor necrosis factor receptor superfamily member 16

1

0

High-throughput

0.486

High

787284

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.486

High

822580

MASP1
Mannan-binding lectin serine protease 1

1

0

High-throughput

0.486

High

1040499

SNX1
Sorting nexin-1

1

0

High-throughput

0.486

High

1075298

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.486

High

1217521

TIAM2
Rho guanine nucleotide exchange factor TIAM2

1

0

High-throughput

0.486

High

1243730

PPHLN
Periphilin-1

1

0

High-throughput

0.486

High

1028410

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

0

Small-scale

0.480

High

1272249

NUB1
NEDD8 ultimate buster 1

1

0

Small-scale

0.480

High

177704

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

Small-scale

0.479

High

398057

ISG15
Ubiquitin-like protein ISG15

1

6

Small-scale

0.479

High

639783

IKBA
NF-kappa-B inhibitor alpha

1

1

Small-scale

0.479

High

1077055

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

1138846

OTU1
Ubiquitin thioesterase OTU1

1

1

Small-scale

0.479

High

1148157

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1204803

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.479

High

1272225

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.479

High

1272233

ASPC1
Tether containing UBX domain for GLUT4

1

1

High-throughput

0.479

High

1272241

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

244737

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

295078

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

299961

ERLN2
Erlin-2

1

0

Small-scale

0.458

High

429096

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.458

High

449784

HMGB1
High mobility group protein B1

1

0

High-throughput

0.458

High

452255

HMOX1
Heme oxygenase 1

1

0

Small-scale

0.458

High

532587

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

533326

PLST
Plastin-3

1

0

High-throughput

0.458

High

535505

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.458

High

543052

GLNA
Glutamine synthetase

1

0

Small-scale

0.458

High

546870

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

568753

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

Small-scale

0.458

High

622607

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

740026

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.458

High

779846

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

943876

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.458

High

974962

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

998946

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1027741

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.458

High

1031243

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

1049104

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1063532

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1064554

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1192149

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1206013

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

1251996

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.458

High

1272227

IFT74
Intraflagellar transport protein 74 homolog

1

0

High-throughput

0.458

High

1272231

SELS
Selenoprotein S

1

0

Small-scale

0.458

High

1272235

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

1272242

HERC5
E3 ISG15--protein ligase HERC5

1

0

Small-scale

0.458

High

1272247

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

965780

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1056301

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

2

Small-scale

0.437

High

1067561

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.437

High

1171083

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

575810

VINC
Vinculin

1

0

High-throughput

0.426

High

134670

NPT3
Sodium-dependent phosphate transport protein 3

2

0

High-throughput

0.328

High

1188343

ATG9A
Autophagy-related protein 9A

2

0

High-throughput

0.328

High

1240029

UBAC2
Ubiquitin-associated domain-containing protein 2

2

0

High-throughput

0.318

High

49481

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

622700

ERD21
ER lumen protein-retaining receptor 1

1

0

High-throughput

0.279

Low

946423

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

1128836

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

1217370

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1224208

S22AF
Solute carrier family 22 member 15

1

0

High-throughput

0.279

Low

1272229

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1272237

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.279

Low

1272248

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

0

High-throughput

0.279

Low

894885

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.269

Low

336937

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.265

Low

344536

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.265

Low

836356

GRAK
Granzyme K

1

0

Small-scale

0.261

Low

47951

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.249

Low

168273

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.249

Low

329868

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

719758

RADI
Radixin

1

0

High-throughput

0.249

Low

1002125

TMM62
Transmembrane protein 62

1

0

High-throughput

0.249

Low

1272230

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.249

Low

1272236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1272239

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

353979

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.238

Low

1241557

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024