HitPredict

Interactor 1: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PK_Tyr_Ser-Thr~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 647 Hs			1 783
+	Hs
		710637 EPHA3_HUMAN (7-642): 3.74e-137: 427: 16.81		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		710848 EPHB2_HUMAN (14-622): 1.12e-131: 414: 18.69		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		710320 EPHA2_HUMAN (14-644): 1.66e-128: 404: 18.67		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		401028 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		931958 EPHB4_HUMAN (140-636): 2.13e-109: 354: 22.16		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		521381 ARAF_HUMAN (83-642): 2.27e-110: 346: 21.83		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		597896 FER_HUMAN (326-611): 1e-97: 319: 31.12		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		186511 EPHA2_HUMAN (14-644): 1.66e-128: 404: 18.67		TRI18_HUMAN (107-776): 9.8e-141: 431: 24.12
+	Hs
		401124 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		TRI22_HUMAN (201-774): 1.33e-95: 308: 13.52
+	Hs
		710888 EPHB2_HUMAN (14-622): 1.12e-131: 414: 18.69		TRI54_HUMAN (198-528): 1.12e-73: 245: 20.71
+	Hs
		279016 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		TRIM3_HUMAN (190-767): 2.94e-78: 269: 14.85
+	Hs
		400818 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		TRI14_HUMAN (301-760): 1.24e-71: 243: 17.80
+	Hs
		400916 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		LIN41_HUMAN (192-513): 3.72e-27: 120: 20.43
+	Hs
		400258 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		RO52_HUMAN (112-378): 2.43e-12: 72: 9.29
+	Hs
		400829 RAF1_HUMAN (83-646): 3.64e-119: 370: 18.47		TRI25_HUMAN (1-158): 2.11e-11: 69.3: 12.66
+	Hs
		521199 ARAF_HUMAN (83-642): 2.27e-110: 346: 21.83		RO52_HUMAN (112-378): 2.43e-12: 72: 9.29