HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: SCIN (Q9Y6U3)
Scinderin (Adseverin)
Gene: SCIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 715
+	Hs
		413883 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413803 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413814 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		924532 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		411699 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		313798 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73
+	Hs
		448963 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		VILI_HUMAN (19-418): 9.15e-73: 254: 30.94
+	Hs
		313728 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73