HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NUP57 (P48837)
Nucleoporin NUP57 (Nuclear pore protein NUP57)
Gene: NUP57

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.50	0.589

Property	Details
Experiments	11283351, 11387327, 9368759
Identification Methods	two hybrid pooling approach, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 541
+	Hs
		162924 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP54_HUMAN (159-535): 2.87e-90: 288: 17.83
+	Sc
		676198 XPO1_YEAST (1-1084): 0: 833: 100.00		NU145_YEAST (4-393): 1.5e-42: 165: 21.52
+	Hs
		162539 XPO1_HUMAN (3-1084): 0: 854: 46.40		SC24C_HUMAN (4-306): 2.13e-34: 140: 11.44
+	Xl
		1145048 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q641I5_XENLA (6-361): 4.3e-28: 121: 16.10
+	Hs
		162244 XPO1_HUMAN (3-1084): 0: 854: 46.40		GANP_HUMAN (6-291): 5.72e-27: 118: 14.00
+	Hs
		162534 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP98_HUMAN (68-329): 1.41e-14: 79.4: 16.10
+	Sc
		676117 XPO1_YEAST (1-1084): 0: 833: 100.00		NU159_YEAST (5-321): 5.81e-20: 96.3: 15.46
+	Hs
		162448 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU214_HUMAN (17-255): 5.03e-10: 64.6: 22.76
+	Hs
		162517 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46
+	Sc
		676300 XPO1_YEAST (1-1084): 0: 833: 100.00		NU100_YEAST (12-279): 1.74e-12: 72.4: 29.41
+	Sc
		675908 XPO1_YEAST (1-1084): 0: 833: 100.00		SLA1_YEAST (3-292): 4.47e-12: 71.2: 16.43
+	Sc
		676294 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP49_YEAST (45-298): 1.04e-09: 62.8: 23.11
+	Sc
		676301 XPO1_YEAST (1-1084): 0: 833: 100.00		NU116_YEAST (1-282): 6.89e-09: 60.8: 22.95
+	Tt
		101847 G0RZB7_CHATD (10-1084): 0: 779: 50.19		NU145_CHATD (33-307): 4.22e-12: 71.3: 23.83
+	Hs
		834682 XPO7_HUMAN (11-1030): 8.18e-147: 469: 13.59		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46
+	Hs
		858024 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NUP98_HUMAN (68-329): 1.41e-14: 79.4: 16.10
+	Hs
		727340 TNPO3_HUMAN (8-1040): 5.86e-127: 412: 13.31		NU214_HUMAN (17-255): 5.03e-10: 64.6: 22.76
+	Hs
		727300 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NU214_HUMAN (17-255): 5.03e-10: 64.6: 22.76
+	Hs
		834652 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46
+	Xl
		1137359 Q5U4V0_XENLA (21-967): 1.15e-120: 394: 12.31		NU153_XENLA (8-286): 7.32e-09: 60.8: 14.84