HitPredict

Interactor 1: HIRA (P54198)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30804502, 33961781, 21724829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1017 Hs			1 103
+	Sc
		381951 HIR2_YEAST (173-1014): 6.81e-99: 333: 16.03		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Hs
		979584 CAF1B_HUMAN (1-520): 9.22e-90: 299: 23.15		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Sc
		381950 HIR1_YEAST (1-856): 8.32e-90: 307: 18.05		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Sc
		382323 CAF1B_YEAST (1-423): 7.19e-88: 292: 20.29		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Hs
		980286 WDR33_HUMAN (1-201): 3.39e-33: 141: 18.32		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		980280 TBL1R_HUMAN (159-398): 3.37e-34: 140: 13.84		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		261392 TBL1X_HUMAN (168-360): 7.87e-23: 106: 18.67		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		964819 WDR5_HUMAN (565-854): 3.71e-18: 88.8: 8.11		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		980544 WDR3_HUMAN (370-855): 5.28e-17: 88.4: 8.14		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		980117 SNR40_HUMAN (4-157): 1.31e-13: 75.7: 18.59		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		284937 TAF5L_HUMAN (103-246): 2.85e-09: 63.2: 30.67		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Dm
		54157 A1Z898_DROME (721-884): 4.49e-09: 62.6: 9.69		H4_DROME (1-103): 4.53e-48: 150: 99.03