HitPredict

Interactor 1: ATN1 (P54259)
Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)
Gene: ATN1

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	16713569
Identification Methods	pull down, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1190 Hs			1 1116
+	Hs
		928324 ATN1_HUMAN (1-1190): 1.01e-149: 482: 100.00		MAGI1_HUMAN (1-537): 7.48e-44: 176: 12.32
+	Hs
		928319 ATN1_HUMAN (1-1190): 1.01e-149: 482: 100.00		ITCH_HUMAN (11-246): 4.77e-29: 127: 16.95
+	Hs
		131854 ATN1_HUMAN (1-1190): 1.01e-149: 482: 100.00		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		928343 ATN1_HUMAN (1-1190): 1.01e-149: 482: 100.00		WWP1_HUMAN (6-240): 4.44e-23: 108: 15.48
+	Hs
		132138 Q86V38_HUMAN (1-1190): 1.98e-148: 479: 98.83		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		215931 SYNJ1_HUMAN (33-453): 9.26e-13: 75.1: 12.33		PKHA7_HUMAN (2-1059): 1.41e-137: 446: 27.40
+	Dm
		119660 M9PB30_DROME (590-1133): 2.6e-11: 70.7: 11.74		M9PB30_DROME (261-1108): 1.32e-81: 296: 12.01
+	Hs
		1140288 CIC_HUMAN (25-764): 2.05e-09: 64.4: 10.38		ACAP2_HUMAN (73-689): 4.4e-59: 220: 13.91
+	Hs
		903188 SMCA2_HUMAN (208-500): 1.57e-13: 78: 15.15		MPRIP_HUMAN (79-765): 7.82e-54: 206: 12.95
+	Hs
		590343 MUC1_HUMAN (293-1133): 5.23e-41: 166: 14.00		WWP1_HUMAN (6-240): 4.44e-23: 108: 15.48
+	Hs
		1406490 ATX2_HUMAN (15-770): 1.22e-27: 123: 10.45		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		1253872 SRCAP_HUMAN (179-1014): 2.44e-20: 100: 11.76		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		132255 ATX2_HUMAN (15-770): 1.22e-27: 123: 10.45		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		1129747 MDC1_HUMAN (99-1036): 6.17e-15: 82.6: 10.11		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		903251 SMCA2_HUMAN (208-500): 1.57e-13: 78: 15.15		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		903483 SMCA4_HUMAN (216-592): 1.32e-10: 68.3: 13.53		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		131836 SMCA2_HUMAN (208-500): 1.57e-13: 78: 15.15		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Dm
		1486711 Q9VUH6_DROME (303-776): 6.09e-10: 66.2: 13.67		SUDX_DROME (1-240): 2.27e-26: 118: 16.21
+	Hs
		131837 SMCA4_HUMAN (216-592): 1.32e-10: 68.3: 13.53		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		131637 SC24D_HUMAN (162-388): 1.98e-10: 67.5: 24.32		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80