HitPredict

Interactor 1: CSK2B (P67870)
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)
Gene: CSNK2B

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27705803, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 406
+	Mm
		931975 CSK2B_MOUSE (1-215): 2.27e-138: 387: 100.00		RING2_MOUSE (8-406): 2.94e-100: 303: 54.25
+	Hs
		931811 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		717673 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		718388 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		PCGF2_HUMAN (31-377): 1.44e-41: 151: 14.37
+	Hs
		931839 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		931825 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		931665 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		PCGF3_HUMAN (34-224): 6.2e-39: 141: 17.53
+	Hs
		749358 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		931709 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33
+	Dm
		437160 CSK2B_DROME (1-215): 1.94e-134: 378: 88.37		Q9VV77_DROME (33-129): 1.77e-37: 137: 27.00