Interactor 1: EPHB3 (P54753)
Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)
Gene: EPHB3
Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.740 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9707552 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~fn3, PDZ~SAM_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
